You can't really omit Ganondorf from a Zelda game, unless they were going to do something similar to Majora's Mask. If there was no Ganondorf, it would break the Triforce link. Who would have the Triforce of Power then? I know they could just make a new villain, but I don't think it would be the same.
As for things I don't want in a new Zelda game, it's harder to think of things I don't want rather than things I do want, but here's my list:
No more characters acting super ridiculous without a good reason ~ Like Tingle. Or basically any character that flails and screams without being in pain. It's good to have funny characters (and I want them in a future game), but these types are just embarrassing to watch.
No G-rating ~ Wow. Judging by the previous posts, I'm going to be unpopular for saying this. I'm not asking for a bloodbath or a really adult storyline. I would just like a bit more realism and more complicated themes being explored in the story.
No Dead World ~ A real kingdom would be much bigger and would have more villages. Hyrule should feel like a living, breathing world. Also, a bigger overworld would mean more opportunities for exploration and for discovering secrets, which is the main aspect of the Zelda series, isn't it?
Recycling gameplay elements might be a problem, but if you take some of those away, it wouldn't be Zelda. Also, voice acting would be nice, but not really necessary. And voice acting in games is still a really risky move, so why take a chance when it works fine as it is?