Also, someone on ZeldaWiki posted another theory, that maybe "Its name may also derive from the phrase "world terminus" used to describe places where one can access many other areas (e.g. a hub area, such as Hyrule field) and may also refer to Termina's compass-like geography." -
ZeldaWiki
...That makes me think of the part at the very start as you travel to clocktown down that twisted passageway... I think it's suggesting maybe Termina's the place that joins other lands together (and if that ended, that would be like the end of the world etc)
But I don't know... I still lean towards the fact it's probably just some general foreshadowing at the fact it's fated to be destroyed unless you do something about it XDD Interesting idea though~