If it is something that people laugh at me for, and I find it funny, then I laugh with them. I find it really helps get over it if you laugh about it. It also causes people to have less of a chance of making fun of you for it, since they know you just don't care.
Although, if it is something that is extremely humiliating, and I can't really handle it, then I lock myself out. I put in my headphones, and just do my own thing. That way, I can think about what I want, without constantly hearing people talk about that moment. If I can't hear them, then it is much easier for me to take my mind off it. Plus, music helps me thing.