Actually, as a left-handed person, I would have been much more comfortable with a lefty option.
I've been playing with the Wiimote in my left hand ever since I got the console, and this is because I always had a harder time pointing with my right. And I'm good at using the nunchuk with my right hand because plenty of old controllers have some type of analog stick for each thumb. I've always held them backwards. I'm used to that.
I would like to point out that holding the Wiimote in my left hand anyway will likely not produce the same results as holding it in my right hand. Imagine if I wanted to swing right. For me, that would be inward. For the right-handed Link on the screen, that would be outward. I'd probably wind up missing a lot unless I swung with the intention of hitting a monster off to my right. In short, the sword play will be awkward. This was not a problem with Twilight Princess, which was merely ported and flipped and given different controls that did not require precise motions.
And this has less to do with gameplay, but Link was always one of my favorite lefty heroes.
Now don't get me wrong. I'm dying for this game to come out and I'm excited for the November release. I'm especially thrilled with all the Hyrulean history we'll finally get to see. But I think they could have taken lefties into consideration when they started this, and I hope they will next time.