Well, after looking up a couple of memes I finally got the hang of it. One thing I noticed about all memes is that it can be usable by a lot of people; not just those who actually know what the picture is. The meme also has to be reusable in a lot of topics, not just in that particular category. If you search some popular memes, you'll know what I mean.
First Meme: Yay Link
This is a shot from the Twilight Princess Parody: A Twilight Problem. You use this when you are expressing your "happiness" about something:
Second Meme: . . .What?
You use this when you are stumped about something. Screenshot from Twilight Princess when Link first discovers Ooocco.
I thought they were pretty funny, and also something that everyone can use.