I would enjoy seeing Zant return for a game, or at the very least mentioned somewhere other than Twilight Princess. I thought that he had the potential of being a very good villain, and was a great villain in Twilight Princess up to the point when Ganondorf was revealed, and he took his clothes off. Before this point he seemed very frightening and powerful, and also very emotionless. He felt absolutely no remorse for what he did. He was definitely a very interesting character.
As much as I would like to see him return, I think it might be better if he didn't. I think that Twilight Princess' story and characters should be left alone.