If not disabling the reaction system, I think because the Mature Discussion board already has its own set of stricter rules, they could be updated to reflect trolling via the reaction system. While I do agree with Minish that these type of things happen in different sections as well, the MD has a very different tone and environment, and it's a bit different for someone to "haha" someone who is being dead serious about a personal belief, than it is to "haha" someone for saying something about a video game. There is no genuine use for "haha" in the MD; as no one should be trying to make a funny post in the first place. Laughing at people for posting something, regardless if you think it's stupid, isn't really a good way to promote healthy discussion, and we've encountered the reaction system abuse in the MD be the cause of several arguments in the past.
I agree that disabling the system in the MD should be something look into at the very least--if it is possible to be disabled specific subform anyway. But there are also other options available to consider, but this would require a lot of vigilance to ensure the abuse is not occurring. Something definitely should be done to keep this form of baiting to a minimum in general though, as it does take a great amount of courage to post in the MD in the first place. You're making yourself vulnerable for sharing your beliefs and being laughed at is not constructive whatsoever.